High salts intake, cardiovascular system and kidney in spontaneous hypertensive rats
نویسندگان
چکیده
منابع مشابه
High salt intake impairs vascular nitric oxide/cyclic guanosine monophosphate system in spontaneously hypertensive rats.
In aortas of spontaneously hypertensive rats (SHRs), excessive dietary salt causes down-regulation of soluble guanylate cyclase (sGC) followed by decreased cyclic GMP production, which leads to impairment of the vascular relaxation response to nitric oxide (NO). The present study aimed to elucidate whether this impaired NO/cyclic GMP system results secondarily from increased blood pressure or f...
متن کاملAmygdala centralis cardiovascular response to angiotensin I microinjection in Goldblatt hypertensive rats
Previous studies have shown that induction of 2kidney -1clip Goldblatt hypertension (2K-1C) induction in rats eliminates hypertensive response after inactivating of the central nucleus of the amygdale (ACe). The present study investigated the possibility of alteration in local renin angiotensin system (RAS) activity in ACe after hypertension induction. Clamps were placed on the left renal arter...
متن کاملAmygdala centralis cardiovascular response to angiotensin I microinjection in Goldblatt hypertensive rats
Previous studies have shown that induction of 2kidney -1clip Goldblatt hypertension (2K-1C) induction in rats eliminates hypertensive response after inactivating of the central nucleus of the amygdale (ACe). The present study investigated the possibility of alteration in local renin angiotensin system (RAS) activity in ACe after hypertension induction. Clamps were placed on the left renal arter...
متن کاملCardiovascular effects of standardized hydroalcoholic extract of Ribes khorasanicum fruit in acute hypertensive rats
Objective: Ribes khorasanicum (R. khorasanicum)traditionally has been used for the treatment of higher blood pressure. In this study, the effect of hydroalcoholic extract of R. khorasanicum fruit in normotensive and hypertensive rats was evaluated. Materials and Methods: Animals were assigned into the following groups: 1) Control, 2) AngII (50 ng/kg), 3) ...
متن کاملEstradiol increases salt intake in female normotensive and hypertensive rats.
The objective of this study was to examine whether or not estradiol (E2) alters sodium intake in hypertensive and normotensive female rats. It was hypothesized that higher doses of E2 would increase sodium consumption and that this response would be greater in spontaneously hypertensive rats (SHR) compared with Wistar Kyoto (WKY) rats. The study involved female SHR and WKY (n = 12/group). All a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Regional blood circulation and microcirculation
سال: 2017
ISSN: 1682-6655
DOI: 10.24884/1682-6655-2017-16-3-62-69